No doubt everyone knows who Oprah Winfrey is. Her show is on every day of the regular week at 4:00 Eastern Time on ABC. Oprah has a range of topics that she'll include in her talkshow, such as "Oprah's Favorite Things" to "The Education Crisis Facing America's Schoolchildren". Regular guests include Nate, the designer, and her best friend, Gayle, who will sometimes even do segments for her.

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